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A woman with reddish nodule on the skin of the breast

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Unknown: A woman with reddish nodule on the skin of the breast
Jose Aneiros-Fernandez MD1, Salvador Arias-Santiago MD2, Ricardo Sotillo MD1, Salomon Menjon-Beltran MD3, Angel Concha MD PhD1
Dermatology Online Journal 17 (2): 11

1. Department of Pathology, University Hospital Virgen de las Nieves, Granada, Spain.
2. Department of Dermatology, University Hospital, Granada, Spain
3. Department of Gynecology and Obstetrics, University Hospital Virgen de las Nieves, Granada. Spain

Case synopsis

Figure 1 Figure 2
Figure 1. Showed a lesion exophytic, lobed, ulcerated and bleeding at the touch

Figures 2 and 3. Histologic sections

Figure 4. Immunohistochemical staining (A) CD31 and (B) D2-40

Figure 3 Figure 4

A 54-year-old woman presented a peri-areolar nodule located in the skin of the right breast. Clinical examination showed a 6 x 5 cm exophytic, lobed, ulcerated, and bleeding nodule (Figure 1). The patient reported that the tumor had grown gradually over a period of 3 months. The patient had been diagnosed 8 years prior to presentation with infiltrating ductal carcinoma of the right breast (pT2NO). This tumor was treated with partial mastectomy (conservative surgery) and lymph node dissection, then subsequently received 30 tangent field radiotherapy sessions to the breast for a total dose of 45 Gy. The rest of her cutaneous exam was normal. There was no family history of any similar tumor. Histological sections are show in Figures 2, 3, and 4.

What is the diagnosis?


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