Hydroxyurea-induced amyopathic dermatomyositis presenting with heliotrope erythema
- Author(s): Ito, Eri;
- Muro, Yoshinao;
- Shibata, Akitaka;
- Sugiura, Kazumitsu;
- Akiyama, Masashi
- et al.
Published Web Locationhttps://doi.org/10.5070/D3208023534
Hydroxyurea (HU) is a chemotherapeutic agent used for the treatment of myeloproliferative disorders such as chronic myeloid leukemia, polycythemia vera, and essential thrombocytosis. We describe a 69-year-old man who had essential thrombocytosis and developed amyopathic dermatomyositis after long-term HU therapy. He presented with Gottron papules and heliotrope erythema. The former has been described in all cases of HU-induced dermatomyositis; the latter has been seen in a few cases of that disorder.