answer in text
graphic question

Gianotti-Crosti Syndrome

Patient's Course
On follow up examination one week later his eruption had almost completely cleared.
Gianotti-Crosti Syndrome: a reactive exanthem
associations Hepatitis B1
Epstein-Barr virus2
coxsackie virus3
parainfluenza virus4
clinical characteristics mostly ages 2-6
predominantly acral papules
often lymphadenopathy
resolves in 3-5 weeks
laboratory evaluation lymphocytosis (54-73%)
increased liver enzymes4
histopathology lymphocytic perivascular infiltrate
papillary dermal edema
Because of the association with known viruses, it is essential to perform appropriate serologic tests. Hepatitis B, in particular may be present without any other signs or symptoms of infection.
1)Gianotti F. Rilievi di una particolare casistica tossinfettiva caratterizzata de eruzione eritemato- infiltrativa desquamativa a focolai lenticolari, a sede elettiva acroesposta. G Ital Dermatol 1955;96:678-97. 2)Lowe L, Hebert AA, Duvic M. Gianotti-Crosti syndrome associated with Epstein-Barr virus infection. J Am Acad Dermatol 1989;20:336-8. 3)Taieb A, Plantin P, du Pasquier P, et al Gianotti-Crosti syndrome: a study of 26 cases. Br J Dermatol 1986;115:49-59. 4)Spear KL, Winkelmann RK. Gianotti-Crosti Syndrome. Arch Dermatol1984:1120:891-896.