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Sorafenib Induced Eruptive Melanocytic Lesions

  • Author(s): Uhlenhake, Elizabeth E.;
  • Watson, Alice C.;
  • Aronson, Peter
  • et al.
Abstract

Sorafenib is a multikinase inhibitor FDA-approved for the treatment of advanced renal cell and hepatocellular carcinoma. Dermatologic side effects include hand-foot skin reaction, facial and scalp erythema and desquamation, splinter subungual hemorrhages, alopecia, pruritus, xerosis, keratoacanthomas, and squamous cell carcinomas. We report sudden eruption of melanocytic nevi diffusely in a patient receiving sorafenib.

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