Benign familial pemphigus ( Hailey-Hailey disease)
- Author(s): White, Forrest;
- Shvartsbeyn, Marianna;
- Meehan, Shane A;
- Urbanek, Richard W
- et al.
Published Web Locationhttps://doi.org/10.5070/D32112029534
A 56-year-old man presented with a 15-year history of scaly red plaques on the trunk and axillae. Skin biopsy was consistent with Hailey-Hailey disease. His condition was refractory to multiple therapies, which included topical and oral antibiotics and topical, intralesional, and oral glucocorticoids. Treatment with subcutaneous botulinum toxin type A at the axillae and on the back led to a nearly complete resolution of plaques in those areas. Botulinum toxin type A should be considered in patients with extensive Hailey-Hailey disease who are fail traditional therapies.