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Dermatology Online Journal

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Gabapentin-induced aquagenic wrinkling of the palms

  • Author(s): Emiroglu, Nazan;
  • Cengiz, Fatma P;
  • Su, Ozlem;
  • Onsun, Nahide
  • et al.
Abstract

Aquagenic keratoderma (AK) or aquagenic wrinklingis a rare palmoplantar skin disease. It is sporadic orhereditary condition. It appears in childhood or youngadulthood and it is seen as multiple asymptomaticsmall shiny papules on the peripheral margin ofpalms and/or soles after submersion in water. Thepathogenesis and etiology of ASA remains unclear.Drugs sometimes trigger AK. Herein, we present thecase of a 29-year-old man who had begun treatmentwith gabapentin three weeks before the onset of hiscutaneous symptoms.

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