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Dermatology Online Journal

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Infantile myofibromatosis – a clinical and pathological diagnostic challenge


Infantile myofibromatosis is a rare disorder offibroblastic/myofibroblastic proliferation andrepresents the most frequent type of mesenchymaltumor in the neonatal period and primary infancy.Three clinical types have been described: solitary,multicentric, and generalized (with visceralinvolvement). A correct characterization of thehistopathology is essential to diagnose theseneoplasias in early infancy. We present a case ofmulticentric infantile myofibromatosis with regressionover time.

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