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Nevus lipomatosus superficialis

  • Author(s): Kim, Randie H;
  • Stevenson, Mary L;
  • Hale, Christopher S;
  • Meehan, Shane A;
  • Chernoff, Karen;
  • Schaffer, Julie V
  • et al.
Abstract

Nevus lipomatosus superficialis is an uncommon cutaneous hamartoma that is characterized by the presence of adipose tissue within the reticular dermis. We describe a 15-year-old boy with a three-year history of the classic type of nevus lipomatosus superficialis, which presented as linear arrays of soft, cerebriform papulonodules and plaques in the right inguinal fold. Investigation for chromosomal aberrations and dysregulation of Wnt signaling may provide insights into the pathogenesis of this hamartoma. Treatment is usually with surgical excision although successful use of other modalities has been described.

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