Tables

Characteristic

Unexposed Group (n=10)

UV Exposed Group (n=11)

Mean age in years (SD)

30.4(5.6)

38.0(8.2)

Male/Female

3/8

4/7

Skin Type II/Skin Type III

9/2

10/1

Mean # of instances of mild erythema during 10 UV treatments per subject (SD)

N/A

1.8(1.1)

Mean # of instances of moderate erythema during 10 UV treatments per subject (SD)

N/A

0.3(0.6)

Table 1.  Description of study exposure groups (Taken from Whitmore, et. al. suntan parlor study, Photochem Photobiol, 2000 71: 700-705).

 

Urine Sample #:

Day 0

Day 1

 

 

 

 

 

 

 

 

 

 

 

 

Day 10

Exposure #:

1

2

3

x

X

4

5

6

7

8

x

x

9

10

11

Day:

W

TH

F

Sa*

Su*

M

T

W

TH

F

Sa*

Su*

M

T

W

Subject

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1

6

7.2

7.2

x

X

8.6

10.4

10.4

12.4

X§

x

x

12.4

15

15

2

6

7.2

8.6

x

X

10.4

12.4

15

15

15

x

x

15

15¨

15

3

6

7.2

8.6

x

X

10.4

12.4

15

15

15

x

x

15

15

15

5

6

7.2

8.6

x

X

10.4

10.4

10.4

12.4

12.4

x

x

15

15

15

10

6

7.2

8.6

x

X

10.4

12.4

15

15

15

x

x

15

15

15

11

6

7.2

7.2

x

X

7.2

8.6

8.6

10.4

12.4

x

x

15

15

15

12

6

7.2

8.6

x

X

10.4

12.4

15

15

15

x

x

15

15

15

13

6

7.2

8.6

x

X

10.4

12.4

15

15

15

x

x

15

15

15

14

6

7.2

7.2

x

X

8.6

X

8.6

10.4

12.4

x

x

15

X§

15

18

6

7.2

8.6

x

X

X§

10.4

12.4

15

15

x

x

15

15

15

20

6

7.2

8.6

x

X

8.6

10.4

10.4

10.4

12.4

x

x

15

15

15

 

Table 2.  UV exposure time (minutes) administered and urine samples collected.  *  No treatments were administered on Saturday and Sunday during the study; §  Missed due to illness; ¨ 50% dose (15 min. back; 0 min. front) due to illness.

 

 

Biomarker

 

UE0

n=10

UE10

n=10

E0

n=11

E1

n=11

E10

n=11

UCA Ratio

Mean

0.044

0.059

0.060

0.285

0.369

SD

0.016

0.028

0.043

0.100

0.163

 

 

 

 

 

 

 

cisUCA (pmol)/ Cr(umol)

Mean

0.452

0.544

0.373

2.363

1.954

SD

0.157

0.303

0.166

1.080

0.622

 

 

Table 3.  UCA ratio and cis-UCA-Cr in control and exposed study groups.   Note: 21 of the total 53 samples had cis-UCA values below the LOD.  All of these samples were from the UV unexposed groups (8 from UE0, 7 from UE10) or from the pre-exposure group (6 from E0).  For statistical purposes, these observations were assigned a value of 3.6 pmol [= L.O.D./√2].