Table 1. Treatment of patch-stage mycosis fungoides by 308-nm excimer laser: Patients 1 and 2.



Treatment Site
(MF Stage IA)


Number of Sessions


Date Treatment Sessions Began (mo/yr)


mJ/cm2 per Session (Range)


Cumulative Dose (J/cm2)



Histologic Response

Follow Up: Clinical Assessment
(6 mo/1 yr)

Patient 1

Right thigh

 

14

 

Mar/2005

 

100 – 300

 

3.25

 

Negative

 

Clear/Pending*

Patient 2

Right posterior waist

Right torso

16

Jun/2004

150 – 1000

9.9

 

Positive

Negative

 

N/A

Clear/Clear

Right posterior waist (retreatment)

Right thigh

 

14

 

Aug/2004

 

150 – 450

 

7.5


Positive

Negative


N/A

Clear/Clear

Right posterior waist (retreatment)

8

Oct/2004

200 – 600

3.0

Negative

Clear/Relapse

Right thigh (two new patches)

14

Apr/2005

200 – 750

6.7

Negative

Clear/Pending*

Right posterior waist (relapse)

Three new patches:

Right buttock

Left posterior thigh

Right thigh




17




Jan/2006




100 – 400




4.6


Negative

 

Negative

Negative

Negative


Pending**

 

Pending**

Pending**

Pending**

N/A, Posttreatment histology was MF positive; laser sessions continued.
*At the time of this writing, one year had not elapsed since the last treatment session.
**At the time of this writing, six months had not elapsed since the last treatment session.