Primary cutaneous CD8 + peripheral

Primary cutaneous CD8+ epidermotropic cytotoxic T-cell lymphoma

Our case

Unic/doble cutaneous Tumor (facial o neck)

Multiple cutaneous Tumor

Unique cutaneous tumor

No extracutaneous involvement. Absence of clonality in blood and bone marrow

Extracutaneous involvement. Clonality in blood and bone marrow.

Clonality in blood and Bone marrow

No solid metastasis

Solid Metastasis (lung, testis, central nevous system, lymph nodes)

No solid metástasis

No epidermotropism (zona Grenz)

Epidermotropism

Epidermotropism

CD8+, CD4-, CD45RA+

CD8+, CD4-, CD30+, CD45RA+, CD7+,CD2-

CD8+,CD4-,CD45RA+, CD7-, CD5+

Ki 67 < 10

Ki 67 >60

Ki 67 40

Good response to local Radiotherapy

Poor response to Radiotherapy and Chemotherapy

Good response to rt and qt

5- year survival rate 60-80%.

5- year survival 20-32 months

Disease-free 5 years after onset