Table 1: Cutaneous sarcoidosis preceding development of neoplasia.

 

 

Reference

Age

Evidence of sarcoidosis

Time

Associated malignancy

Atwood WG (1966) [21]

49 BM

LNp, lung, chest wall, spleen

6 yr

MF & lymphocytic lymphoma

Asvesti C (1994) [22]

52 F

LNp, hilar LN, ACE lung (int) hepatomeg, Inc ESR

~8 mo

Sweat gland carcinoma

Banno S (1992) [23]

31 M

LNp, muscle

13 yr

DLBCL

Bessis D (1996) [24]

35 F

  -

27 yr

MF and anaplastic large TCL (Ki 1+)

Brechtel B (1996) [25]

 57 F

  -

1 yr

Breast cancer

Cantwell AR (1982) [26]

73 WF

Lung (interstitial), ACE

14 mo

NHL (poor diff, immature), Lip BCC

Caras W (2003) [27]

Patient 1

32 BM

Hilar LN, ACE

6 yr

HD (nodular sclerosis)

Chao SC (2000) [28]

Case 1

42 M

 Lung (interstit)

14 yr

CTCL

Collet E (1992) [29]

58 F

Lung (?), cutaneous ( ?)

7 yr

Waldenstrom

Corda L (1996) [30]

65 F

Eyes (b/l uveitis), bronchial, gastric

7 yr

Kaposi’s dx on the skin

Diette KM (1984) [31]

49 M

Liver, BM

1 yr

Intracranial large-cell NHL

Falchero L (1998) [32]

74 F

LNp, lung nodules

3 yr

CTCL

Harada H (1994) [33]

44 F

Lung interstitial

23 yr

CTCL

Hermann C (1980) [34]

60 M

Joints (knee)

4.5 yr

AML

Karakantza M (1996) [35]

34 BM

LNp, hilar LN, monoarthritis, b/l keratoconjunctiv

28 yr

Extramedullary plasmacytoma

Katz KA (2002) [36]

66 F

Skin

3 mo

MDS

* granulomatous skin

Keohane SG (1996) [37]

36 M

Hilar LN

6 yr

Low-grade NHL

Maekawa Y (1993) [38]

53 AF

Hilar LN, lung (int), inc ACE

6 mo

ADK esophagus

Maillard H (1998) [39]

34 M

  -

5 yr

MF

Mainguene C (1993) [40]

 31 F

Arthralgia, ACE, LNp

4 yr

MF

McFarland JP (1978) [41]

47 BF

LNp, hilar LN

8 yr

MF

Morii S (1997) [42]

61 F

Inc ACE

15 mo

Gastric plasmacytoma

Myerson RM (1971) [43]

49 BM

Hilar LN, p LN, lungs, liver, uveitis

23 yr

Hepatocellular carcinoma

Noone PG (1993) [44]

?

Pulm (int), arthralgias

3 yr

NSCLC (ADK)

Okada M (2000) [45]

54 F

P LN, hilar LN, uveitis

2 mo

Colon ADK +

XP &SCC/BCC 6 mo before and coex with sarc.

Oliwiecki S (1992) [46]

49 M

ACE

3 yr

NHL (palate)

Raben AC (1961) [47]

45 F

N/A

?

NHL

Robert C (1997) [67]

35 F

Mediast LN, lung (int), bronch epit

27 mo

Melanoma

Roth D (1994) [48]

31 BM

Lung (int), eye, granul gastritis & proctitis

19 yr

Poorly diff stomach ADK

Schiller G (2003) [49]

71 F

Lung(interstitial), ankle edema, also Eryth Nod

18 mo

Hairy-cell leukemia

Sherertz EF (1986) [50]

54 M

Skin

Shortly

NHL (lymphocytic lymphoma)

Serratrice J (2002) [51]

2 cases

55 BF

b/l eye (uveitis), ESR

7 yr

CMML

62 WF

Uveitis, skin

5 yr

CMML

Simsek S (2002) [52]

51 F

Lung (int), liver, pLN

7 yr

HD

Sorrells T (1997) [53]

39 BM

Hilar LN

3 yr

NHL (MF)

Suarez-Vilela D (2003) [54]

67 F

Skin

2 yr

NHL (AILD-like T-cell lymphoma)

Takada K (1993) [55]

 31 M

Muscle, ACE

23 yr

NHL (supraclavicular LN) (T-cell diffuse large-cell)

Terao S (1985) [56]

 55 F

  -

8 yr

NHL

Todd RF (1980) [57]

78 M

Eye, neurop, hypercalc

3 yr

Prostate cancer

Ueda T (1988) [58]

 54 F

Lung, eye

5 yr

NHL

VesteyJP (1993) [59]

2 cases

66 M

Skin, hematologic

4.5 mo

AML (through MDS)

71 M

Skin, hematologic

4 mo

MDS

Zimmermann-Belsin (2000) [60]

27M

Skin, b/l hilar LN

3 yr

Thyroid papillary carcinoma

 

Present report

(4 cases)

 

 

64 F

LNp, mediast LN, lung interstitial

8 yr

Breast cancer, colon cancer, renal cancer

42 F

LNp, arthritis

4 yr

Breast cancer (bilateral),

SCC skin

41 F

Mediast LN, lung interstitial,

5 yr

Breast cancer (infiltrating ductal carcinoma)

47 M

 

Lung interstitial

15 yr

Prostate cancer