Table 2: Data concerning treatment and outcome in 21 followed-up children with LAD

 

Patient

Age

Sex

Dapsone

(monotherapy)

Dapsone + oral steroids

Dapsone + Erythromycin (50mg/Kg/d)

Amoxicillin

Sulfamide ATB

Duration of treatment

Response to treatment (partial or complete healing)

Flare under ttt

Follow-up

Recurrence

1

6

M

50 mg/d

 

 

 

 

21 mths

3 days

1 episode

2y

No

2

4

F

 

 

 

 

1 g/d

1 y

 

 

2y

No

3

11

F

50 mg/d

 

 

 

 

4 mths

23 days

No

6y

No

4

1.8

F

75mg/d

 

 

 

 

NP

22days

NP

LF

LF

5

6

M

 

50mg/d + 40mg/d

 

 

 

 

9 mths

 

15 days

 

Yes

 

9 mths

 

No

6

1. 5

M

 

 

50mg/d

 

 

2 mths

Rapid response

No

LF

LF

7

2

M

25mg/d

 

 

 

 

NP

?

NP

LF

LF

8

4. 5

M

 

 

75mg/d

 

 

6 mths

24 days

No

4y

No

9

3

M

 

 

25mg/d

 

 

3 mths

NP

Yes

3 mths

LF

10

4

M

 

 

50mg/d

 

 

one

mth

NP

No

3 mths

LF

11

15

M

 

200mg/d + 30mg/d

 

 

 

6 y

11 days

Yes

11 y

No

12

8

M

 

50mg/d+ 10 mg/d

 

 

 

NP

7 days

No

LF

LF

13

2..5

M

 

50mg/d+15mg/d

 

 

 

3 y

Rapid response

Yes

3 y

No

14

1

M

 

25mg/d+10mg/d

 

 

 

9 mths

8 days

Yes

9 mths

No

15

2

M

 

25mg/d+10mg/d

 

 

 

9 mths

15 days

Yes

11 mths

No

16

3

F

 

 

 

1g/d

 

3 mths

20 days

yes

3 mths

Remission then LF

17

12

F

25 mg/d

 

 

 

 

3 mth

No

Yes

3 mths

Continued to flare

18

7

F

 

25mg/d+ 25mg/d

 

 

 

3 mths

15 days

No

2 y

Pruritus

19

8

F

50 mg/d

 

 

 

 

1 year

15 days

No

1. 5 y

No

20

1.5

M

25 mg/d

 

 

 

 

5 mths

9 days

No

4 mths

No

21

11

M

100 mg/d

 

 

 

 

6 mths

7 days

No

3 y

No

 

Abbreviations: y:years ; mth(s): month(s); NP: not precised; LF: lost to follow-up, ttt: treatment