Table  1  : Frequency  distribution of acetylation  phenotype
in AD patient  and  controls  

Acetylation

Phenotype

Subjects

Patients

Controls

Slow

 

N o.

26

29

%

72.2

69.4

Rapid

No.

10

13

%

27.8

30.6

Total

No.

36

42

%

100

100

 
Table   2 : The  mean and range of the concentrations of Dapsone (DDS) and monoacetyldapsone  (MADDS) in  A D  patients  and  controls 

Acetylation

Phenotype

Concentration

mg/dl

Subjects

Patients

Controls

Slow

 

Mean DDS

(Range)

0.82  + 0.31

      (0.45-2.18)

0.87  + 0.23

(0.31 – 2.84)

Mean MADDS

(Range)

0.36  + 0.17

(0.08-0.64)

0.45  + 0.38

(0.09-1.01)

Rapid

Mean DDS

(Range)

0.94 + 0.37

(0.65-1.91)

0.64  + 0.27

(0.57-1.64)

Mean MADDS

(Range)

0.59  + 0.18

(0.20-0.92)

0. 53  + 0.22

(0.21-1.12)