Table 3. Crosslinking of HA Fillers

Crosslinking chemistry

Representative products

BDDE (butanediol diglycidyl ether)

Juvéderm® Ultra,
Juvéderm® Ultra Plus,
Restylane®, Perlane®

DVS (divinyl sulphone)

Prevelle

DEO (1,2,7,8 diepoxyoctane)

Puragen

BCDI (p-phenylene bisetheyl carbodi-imide)

Elevess