I am a 48 year-old female radiologist in excellent health. I am taking no medications and have no history of allergy. I stayed in a rainforest lodge in Costa Rica (near the Panamanian border) about five weeks ago. There was no hot water in the lodge to wash clothes or bedding. Several hours after arriving at the lodge, I noticed red, pimple-like eruptions (resembling bites) distributed primarily around my ankles and lower legs with a few lesions in the inguinal regions bilaterally. These were intensely pruritic. I did not treat them with any medication and traveled back to the States, where the lesions persisted. They became somewhat nodular and were intensely pruritic, especially at night. On numerous occasions, I noted the appearance of numerous, small hives especially posterior to the knee and in the upper inner thigh regions bilaterally. These seemed to disappear by morning. Ten days ago,I had the yellow fever immunization (I plan to travel to Brazil in the near future) and a tetanus booster. I had no immediate allergic reaction to these injections. At the same time (ten days ago), I began treating the skin lesions (which I presumed to be scabies) with 1% Lindane lotion. I did not do a total body application. Rather, I applied the lotion liberally to the lesions on about 4 occasions over a 3 day period of time. The lesions have responded dramatically to this treatment and have almost disappeared at this time. However, over the past 5 days I have experienced numerous areas of urticarial wheals (which come and go at inconstant intervals in a matter of hours) and on one occasion I lost my voice, indicative of mild laryngeal edema. I have not experienced wheezing. I am puzzled by the urticaria since I was experiencing it prior to the yellow fever and tetanus injections.(It is much worse since these injections, however.) Is it unusual to experience numerous areas of urticarial wheals after the lesions of scabies (or other mite infestation) have resolved? Do you know of any information that might be helpful to me in terms of treating (and understanding) this rather complicated medical scenario? Thank you very much for any information that you might be able to provide. (You realize, of course, that radiologists have very little knowledge of the skin! We deal only with its radiologically visible contents!) Jeanne Bullock, MD ========================= From: Haines Ely Dr. Bullock you have chigger bites. These are most common in the rain forest. Expect 3 weeks of itch. Next time spray your ankles and socks with DEET, never sit down without something under you (take a poncho or small tarp to sit on) and spray the tarp with DEET daily. Haines Ely ================= From: bberman@mednet.med.miami.edu I spoke with David Taplin who is quite familiar with that area. He feels : Fleas, chiggers, Cuticoides or sand flies. Minor concern for developing Leishmaniais as well. I wonder if she is allergic to eggs whose antigens are present in the yellow fever vaccine. Brian Berman