NEONATAL LUPUS ERYTHEMATOSUS -------------------------------------------- Anything new in neonatal LE, interesting or anecdotal? The child, 5ms, presented today with erythematous arcuate lesions and fever. He is from Algeria and has sickle-cell trait and an as yet undefined thalessemia. Diane Thaler -------------------- Good review article in new JAAD. Rash should resolve spontaneously by 6 mo. Are you sure it is neonatal LE? I did not think such kids were febrile.If it is, watch both mom and kid for development of LE later. Barbara R. Reed, MD -------------------- Barbara, you are right, I am not sure it is. If it is not, it is an urticarial vasculitis, serum sickness, or leukemia cutis-that is my immediate differential. The fever occurred after the rash onset, so, may be fortuitous, but I worked it up anyway. Also did biopsy. Will report. It is a male, so, the question of RNP instead of SSA/B exists if it is NLE. Diane Thaler --------------------