NECROBIOSIS LIPOIDICA ---------------------------------------------- I've had a couple of cases of BAD ulcerating NLD respond well to cyclosporine, with long-term drug-free remissions. Kevin C. Smith MD FRCPC -------------------- Did both the ulcerations and the NLD lesions go away? Diane Thaler -------------------- I just saw on follow-up a 25 yr old female patient of mine whose NLD on her lower leg has completely resolved after 1 1/2 years use of topical Premarin cream and Westcort (equal parts) nightly for a couple months and then every other night. Philip Hughes, M.D. -------------------- Premarin for NLD is a new one for me. Please expand on its use here....and do you have other interesting dermatologic applications for it as well? Diane Thaler --------------------