DAKINS SOLUTION
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They looked at concentrations of Dakins(.25%, .025%, and .0125%) for 
toxicity and bactericidal efffect. Concentrations of .25% killed both 
healthy cells and bacteria, but only bacteria at .025%.  Dakins at .0125% 
was ineffectivefor killing bacteria.  They concluded that modified 
Dakins(.025%) was the better choice.

Ed Zabawski. DO
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A word to the wise:  when you write for Dakin's 0.25% make sure to write 
it as "1/4%".
In this way the pharmacist won't move the decimal point, and make up a 
2.5 or (shudder) a 25% solution!

Robert I. Rudolph, M.D., FACP
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This actually happened to a patient of mine who was prescribed 0.25% 
phenol in lac hydrin (for itch) and got 25% phenol. Her 85 y/o legs were
peeled/burned severely. Everything came out ok, though. She healed in 
about 2 weeks and has nicer looking skin below the knee than she did 
before.  The pharmacy denied doing it of course.

Guy Webster
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Dakins is a proprietary product( Century Pharmaceuticals) of buffered 
.25% or .5% sodium hypochlorite(NaClO) solution.  For those who are 
interested...

Bactericidal and wound healinf properties of sodium hypochlorite 
solutions:the 1991 Lindberg award.  J Burn Care Rehab Sept/Oct 1991 pp. 
420-424

E. Zabawski, DO, R.Ph
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