COUMADIN From: john_g1@IX.NETCOM.COM (john) I recently saw a 71 year old Chinese man with extensive ecchymoses on the arms and an extensive hx of senile pruritus. His ecchymoses are worrisome to the referring physician who wants to know whether or not to take him off of his coumadin or decrease the dose. He is 6 months status post-CVA. He has already been thru a course of Atarax,and Seldane. The problem is : Is this on the way to a purpura fulminans- should the coumadin be halted?? Would topical or systemic steroids be contra-inidicated with his already thin and fragile skin. any help would be appreciated. John Guagenti,MD. E-mail,or post to group. ===================== From: jeisner@sos.sos.net (Jerry Eisner) If his mouth, legs and fingernails look ok without evidence of petechiae, and if the arm ecchymoses are only on sun exposed areas, ie volar surfaces, I would not see this as a cause to worry about purpura fulminans. If the ecchymoses do not develop into actual hematomata or bleeding, I would use other factors, such as stable hematocrit, lack of GI blood loss, acceptable Protimes, etc to reassure me further. I would not,however, take the hx of "senile pruritis" at face value unless I had satisfied myself that other systemic and local causes of itching had been considered. Jerry Eisner