ANETODERMA
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A 16 year old girl, healthy, no meds, no OCP, not sexually active, presents 
with a two year history of progressive bluish atrophic patches on the arms, 
legs and trunk; approximately currently 20 in all.  Some on very cosmetically 
noticeable areas (neck).  Asymptomatic.  these lesions are not preceded by any 
other primary lesion.

Initial biopsy was done one year ago: dx anetoderma.  Repeat biopsy done one 
month ago: anetoderma.

We have tried topical corticosteroids (mometasone/elocom/elocon), tetracycline 
systemically, minocycline systemically, topical retinoic acid cream. Minimal 
to no response

Current (and so far best) regimen):  minocycline 50 mg BID + Retinoic Acid 
cream 0.025% with mild to moderate induration.  Occasional new lesions arise 
but, older lesions appear a little less noticeable to patient (but not to 
mom).

Any suggestions for diagnostics or therapeutics.


Warren J. Winkelman, MD, FRCPC
Director, Immunodermatology Unit
Department of Dermatology
Montreal General Hospital
Montreal, Quebec, CANADA
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I have a patient with primary anetoderma who is quite badly involved. About
18 mos ago I began plaquenil 200bid. She's actually had no new lesions since,
and an apparant firming-up of many old ones.

Guy Webster MD
Jefferson Med. Coll.
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				4.01.96