Photoessay: The Skin and Diabetes Mellitus
by A Huntley
Dermatology Online Journal, December 1995
Volume 1, Number
2
Granuloma Annulare and Diabetes
Similar to the association of necrobiosis lipoidica and diabetes, it
appears
that a high percentage of persons with disseminated granuloma annulare
have
diabetes mellitus. The individual lesions typically consist of an
annular array
of erythematous to brown and slightly translucent papules.
-
Figs 61,62. Dorsum of the hand of two patients with diabetes
mellitus and
granuloma annulare. The left-hand image demonstrates the annular and
serpiginous nature of the border. The right-hand image is of an
enlarging
papule which is developing a central dell.
That form which is more associated with diabetes is associated with
multiple and
widespread lesions.
-
Figs 63,64. Patient with diabetes mellitus who also has disseminated
granuloma annulare. The left-hand image demonstrates the dispersed
involvement
on the upper back and arm. The right-hand image demonstrates the
multiple brown
to erythematous papules on close-up view.
histology
-
Figs 65,66. Skin biopsy from a patient with diabetes mellitus and
disseminated granuloma annulare. The left-hand image demonstrates both
a
perivascular and interstitial inflammatory cell infiltrate. The
right-hand
image demonstrates histiocytes between collagen bundles.
additional images of granuloma annulare
All contents copyright (C), 1995.
Dermatology Online Journal
University of California Davis
