Table 3: Bioequivalence of SC and IM administration of alefacept

Pharmacokinetic parameter	n	Bioequivalence estimate	90 Percent CI
AUClast , h*μg/ml	42	104	97–112
Cmax, μg/ml	42	96	87–107
AUC¥, h*μg/ml	41^a	103	96–111

AUC_¥, area under the serum concentration-time curve to infinity; AUC_last, area under the serum concentration-time curve to the last measurable value; CI, confidence interval; C_max, peak serum concentration; IM, intramuscular; SC, subcutaneous.

^aExcludes one subject for whom this parameter could not be estimated.