Tables
|
Characteristic |
Unexposed
Group (n=10) |
UV
Exposed Group (n=11) |
|
Mean age
in years (SD) |
30.4(5.6) |
38.0(8.2) |
|
Male/Female |
3/8 |
4/7 |
|
Skin Type II/Skin Type III |
9/2 |
10/1 |
|
Mean # of
instances of mild erythema during 10 UV treatments per subject (SD) |
N/A |
1.8(1.1) |
|
Mean # of
instances of moderate erythema during 10 UV treatments per subject (SD) |
N/A |
0.3(0.6) |
Table 1. Description of study exposure groups
(Taken from Whitmore, et. al. suntan parlor study, Photochem Photobiol, 2000
71: 700-705).
|
Urine Sample #: |
Day 0 |
Day 1 |
|
|
|
|
|
|
|
|
|
|
|
|
Day 10 |
|
Exposure #: |
1 |
2 |
3 |
x |
X |
4 |
5 |
6 |
7 |
8 |
x |
x |
9 |
10 |
11 |
|
Day: |
W |
TH |
F |
Sa* |
Su* |
M |
T |
W |
TH |
F |
Sa* |
Su* |
M |
T |
W |
|
Subject |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1 |
6 |
7.2 |
7.2 |
x |
X |
8.6 |
10.4 |
10.4 |
12.4 |
X¤ |
x |
x |
12.4 |
15 |
15 |
|
2 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
12.4 |
15 |
15 |
15 |
x |
x |
15 |
15¬ |
15 |
|
3 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
12.4 |
15 |
15 |
15 |
x |
x |
15 |
15 |
15 |
|
5 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
10.4 |
10.4 |
12.4 |
12.4 |
x |
x |
15 |
15 |
15 |
|
10 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
12.4 |
15 |
15 |
15 |
x |
x |
15 |
15 |
15 |
|
11 |
6 |
7.2 |
7.2 |
x |
X |
7.2 |
8.6 |
8.6 |
10.4 |
12.4 |
x |
x |
15 |
15 |
15 |
|
12 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
12.4 |
15 |
15 |
15 |
x |
x |
15 |
15 |
15 |
|
13 |
6 |
7.2 |
8.6 |
x |
X |
10.4 |
12.4 |
15 |
15 |
15 |
x |
x |
15 |
15 |
15 |
|
14 |
6 |
7.2 |
7.2 |
x |
X |
8.6 |
X |
8.6 |
10.4 |
12.4 |
x |
x |
15 |
X¤ |
15 |
|
18 |
6 |
7.2 |
8.6 |
x |
X |
X¤ |
10.4 |
12.4 |
15 |
15 |
x |
x |
15 |
15 |
15 |
|
20 |
6 |
7.2 |
8.6 |
x |
X |
8.6 |
10.4 |
10.4 |
10.4 |
12.4 |
x |
x |
15 |
15 |
15 |
Table
2. UV exposure time (minutes) administered
and urine samples collected. * No treatments were administered on Saturday and Sunday during
the study; ¤ Missed
due to illness; ¬ 50% dose (15 min. back; 0 min. front) due to
illness.
|
Biomarker |
|
UE0 n=10 |
UE10 n=10 |
E0 n=11 |
E1 n=11 |
E10 n=11 |
|
UCA
Ratio |
Mean
|
0.044 |
0.059 |
0.060 |
0.285 |
0.369 |
|
SD |
0.016 |
0.028 |
0.043 |
0.100 |
0.163 |
|
|
|
|
|
|
|
|
|
|
cisUCA (pmol)/ Cr(umol)
|
Mean |
0.452 |
0.544 |
0.373 |
2.363 |
1.954 |
|
SD |
0.157 |
0.303 |
0.166 |
1.080 |
0.622 |
Table
3. UCA ratio and cis-UCA-Cr in control and exposed study
groups. Note: 21 of the
total 53 samples had cis-UCA
values below the LOD. All of these
samples were from the UV unexposed groups (8 from UE0, 7 from UE10)
or from the pre-exposure group (6 from E0). For statistical purposes, these
observations were assigned a value of 3.6 pmol [= L.O.D./Ã2].